Roger J. Melton

First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies

Glen J. Weiss, Joseph Chao, Jeffrey D. Neidhart et al. · Investigational New Drugs · 2013 · 220 citations · Full text

Pharmacy, Oncology, Pharmacology +14

Functional Characterization of a Testes-Specific α-Subunit Isoform of the Sodium/Potassium Adenosinetriphosphatase

Gustavo Blanco, Roger J. Melton, Gladis Sánchez et al. · Biochemistry · 1999 · 89 citations

Life Sciences, Cell Biology, Molecular Biology +16

The α4 Isoform of the Na,K-ATPase Is Expressed in the Germ Cells of the Testes

Gustavo Blanco, Gladis Sánchez, Roger J. Melton et al. · Journal of Histochemistry & Cytochemistry · 2000 · 65 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Inhibition of Cytochrome P450 3A4 by a Pyrimidineimidazole:  Evidence for Complex Heme Interactions

J. Matthew Hutzler, Roger J. Melton, Jeanne M. Rumsey et al. · Chemical Research in Toxicology · 2006 · 38 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Nucleotide P2Y1 receptor agonists are in vitro and in vivo prodrugs of A1/A3 adenosine receptor agonists: implications for roles of P2Y1 and A1/A3 receptors in physiology and pathology

Theodore E. Liston, Sonja Hinz, Christa E. Müller et al. · Purinergic Signalling · 2020 · 25 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15