Jennifer Proctor

Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells

Olivier De Henau, Matthew Rausch, David A. Winkler et al. · Nature · 2016 · 865 citations

Medicine, Cancer Biology, Oncology +14

PI3K-δ and PI3K-γ Inhibition by IPI-145 Abrogates Immune Responses and Suppresses Activity in Autoimmune and Inflammatory Disease Models

David G. Winkler, Jonathan P. DiNitto, Janid A. Ali et al. · Chemistry & Biology · 2013 · 258 citations

Life Sciences, Immunology, Pathology +15

Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate

Catherine A. Evans, Tao Liu, André Lescarbeau et al. · ACS Medicinal Chemistry Letters · 2016 · 151 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +11

Inhibition of Hedgehog Signaling Antagonizes Serous Ovarian Cancer Growth in a Primary Xenograft Model

Christopher McCann, Whitfield B. Growdon, Kashmira Kulkarni‐Datar et al. · PLoS ONE · 2011 · 89 citations · Full text

Medicine, Oncology, Pharmacology +15

Hedgehog Pathway Inhibition in Chondrosarcoma Using the Smoothened Inhibitor IPI-926 Directly Inhibits Sarcoma Cell Growth

Veronica T. Campbell, Puviindran Nadesan, Shabana Amanda Ali et al. · Molecular Cancer Therapeutics · 2014 · 78 citations · Full text

Medicine, Oncology, Pharmacology +17