Nature · 2016 · 865 citations · 18 references
MedicineCancer BiologyOncologyCancer ImmunologyImmunotherapyMolecular OncologyCancer ImmunotherapyCheckpoint Inhibitor TherapyImmune Checkpoint InhibitorsImmune Checkpoint ModulationImmune Checkpoint RegulationImmune CheckpointsImmune Checkpoint Blockade ResistanceImmune Checkpoint ResistancePi3k InhibitorsPi3k SignalingResistance To Checkpoint Inhibitors
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Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma
James Larkin, Vanna Chiarion‐Sileni, René González et al. · New England Journal of Medicine · 2015 · 8.1K citations · Full text
Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
Gabriela Bindea, Bernhard Mlecnik, Marie Tosolini et al. · Immunity · 2013 · 4.7K citations · Full text
Medicine, Immunology, Oncology +17
Central Role for G Protein-Coupled Phosphoinositide 3-Kinase γ in Inflammation
Emilio Hirsch, Vladimir L. Katanaev, Cecília Garlanda et al. · Science · 2000 · 1.2K citations
PI3Kγ is a molecular switch that controls immune suppression
Megan M. Kaneda, Karen Messer, Natacha Ralainirina et al. · Nature · 2016 · 1.2K citations