Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell–suppressive activity

Kiavash Movahedi, Martin Guilliams, Jan Van den Bossche, +5

Blood

Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

Kiavash Movahedi, Damya Laoui, Conny Gysemans, +8

Cancer Research

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

Hannah Van Hove, Liesbet Martens, Isabelle Scheyltjens, +17

Nature Neuroscience

Cell LineageDevelopmental BiologySingle Cell SequencingMedicineTissue Environment +5

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

Ana Rita Pombo Antunes, Isabelle Scheyltjens, Francesca Lodi, +25

Nature Neuroscience

GliomaTumor HeterogeneityMacrophage CompetitionMedicineImmunology +8

Tumor Hypoxia Does Not Drive Differentiation of Tumor-Associated Macrophages but Rather Fine-Tunes the M2-like Macrophage Population

Damya Laoui, Eva Van Overmeire, Giusy Di Conza, +14

Cancer Research

Tumor-associated MacrophagesImmunologyBiological MicroenvironmentsPathologyCancer Biology +15

Nanobody-Based Targeting of the Macrophage Mannose Receptor for Effective <i>In Vivo</i> Imaging of Tumor-Associated Macrophages

Kiavash Movahedi, Steve Schoonooghe, Damya Laoui, +9

Cancer Research

Therapeutic depletion of CCR8⁺ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy

Helena Van Damme, Bruno Dombrecht, Máté Kiss, +26

Journal for ImmunoTherapy of Cancer

Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge

Anat Shemer, Isabelle Scheyltjens, Gal Ronit Frumer, +12

Immunity

InflammationCytokineAutoimmune DiseaseMedicineImmunology +6

A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages

Jung‐Seok Kim, Masha Kolesnikov, Shany Peled-Hajaj, +12

Immunity

EpendymaGliomaCns Border-associated MacrophagesMedicineImmunology +7

Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation

Karen De Vlaminck, Hannah Van Hove, Daliya Kancheva, +17

Immunity

NeuroanatomyMedicineImmunologyBrain-immune InteractionNeurology +6