Isabelle Scheyltjens

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

Hannah Van Hove, Liesbet Martens, Isabelle Scheyltjens et al. · Nature Neuroscience · 2019 · 1K citations · Full text

Cell Lineage, Developmental Biology, Single Cell Sequencing +7

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

Ana Rita Pombo Antunes, Isabelle Scheyltjens, Francesca Lodi et al. · Nature Neuroscience · 2021 · 614 citations · Full text

Glioma, Tumor Heterogeneity, Macrophage Competition +10

Therapeutic depletion of CCR8⁺ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy

Helena Van Damme, Bruno Dombrecht, Máté Kiss et al. · Journal for ImmunoTherapy of Cancer · 2021 · 192 citations · Full text

Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge

Anat Shemer, Isabelle Scheyltjens, Gal Ronit Frumer et al. · Immunity · 2020 · 167 citations · Full text

Inflammation, Cytokine, Autoimmune Disease +8

A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages

Jung‐Seok Kim, Masha Kolesnikov, Shany Peled-Hajaj et al. · Immunity · 2020 · 166 citations · Full text

Ependyma, Glioma, Cns Border-associated Macrophages +9