A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

Hannah Van Hove, Liesbet Martens, Isabelle Scheyltjens, +17

Nature Neuroscience

Cell LineageDevelopmental BiologySingle Cell SequencingMedicineTissue Environment +5

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

Ana Rita Pombo Antunes, Isabelle Scheyltjens, Francesca Lodi, +25

Nature Neuroscience

GliomaTumor HeterogeneityMacrophage CompetitionMedicineImmunology +8

Therapeutic depletion of CCR8⁺ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy

Helena Van Damme, Bruno Dombrecht, Máté Kiss, +26

Journal for ImmunoTherapy of Cancer

Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge

Anat Shemer, Isabelle Scheyltjens, Gal Ronit Frumer, +12

Immunity

InflammationCytokineAutoimmune DiseaseMedicineImmunology +6

A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages

Jung‐Seok Kim, Masha Kolesnikov, Shany Peled-Hajaj, +12

Immunity

EpendymaGliomaCns Border-associated MacrophagesMedicineImmunology +7

Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation

Karen De Vlaminck, Hannah Van Hove, Daliya Kancheva, +17

Immunity

NeuroanatomyMedicineImmunologyBrain-immune InteractionNeurology +6

A Tool for Brain-Wide Quantitative Analysis of Molecular Data upon Projection into a Planar View of Choice

Samme Vreysen, Isabelle Scheyltjens, Marie‐Eve Laramée, +1

Frontiers in Neuroanatomy

Evaluation of the expression pattern of rAAV2/1, 2/5, 2/7, 2/8, and 2/9 serotypes with different promoters in the mouse visual cortex

Isabelle Scheyltjens, Marie‐Eve Laramée, Chris Van den Haute, +5

The Journal of Comparative Neurology

GeneticsSynaptic TransmissionRaav SerotypeExpression PatternSynaptic Signaling +22

Identifying the variables that drive tamoxifen‐independent CreERT2 recombination: Implications for microglial fate mapping and gene deletions

Hannah Van Hove, Ana Rita Pombo Antunes, Karen De Vlaminck, +3

European Journal of Immunology

Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq

Viacheslav Mylka, Irina Matetovici, Suresh Poovathingal, +13

Genome biology