Suzanne L. Jacques

PAR1 Is a Matrix Metalloprotease-1 Receptor that Promotes Invasion and Tumorigenesis of Breast Cancer Cells

Adrienne Boire, Lidija Covic, Anika Agarwal et al. · Cell · 2005 · 840 citations · Full text

Medicine, Cancer Biology, Oncology +13

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models

Elayne Chan-Penebre, Kristy G. Kuplast, Christina R. Majer et al. · Nature Chemical Biology · 2015 · 546 citations

Medicine, Medicinal Chemistry, Pharmacology +8

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

K.S. Gajiwala, Joe C. Wu, James G. Christensen et al. · Proceedings of the National Academy of Sciences · 2009 · 386 citations · Full text

Medicine, Oncology, Pharmacology +16

Blocking the Protease-Activated Receptor 1-4 Heterodimer in Platelet-Mediated Thrombosis

Andrew J. Leger, Suzanne L. Jacques, Jehangir Badar et al. · Circulation · 2006 · 218 citations

Medicine, Molecular Biology, Pharmacology +17

Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound

Lorna H. Mitchell, Allison E. Drew, Scott Ribich et al. · ACS Medicinal Chemistry Letters · 2015 · 136 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11