Suzanne L. Jacques

PAR1 Is a Matrix Metalloprotease-1 Receptor that Promotes Invasion and Tumorigenesis of Breast Cancer Cells

Adrienne Boire, Lidija Covic, Anika Agarwal et al. · Cell · 2005 · 836 citations · Full text

Breast Oncology, Medicine, Breast Cancer Cells +9

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models

Elayne Chan-Penebre, Kristy G. Kuplast, Christina R. Majer et al. · Nature Chemical Biology · 2015 · 533 citations

Vitro Potency, Signal Transduction, Medicine +10

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

K.S. Gajiwala, Joe C. Wu, James G. Christensen et al. · Proceedings of the National Academy of Sciences · 2009 · 380 citations · Full text

Kit Kinase Mutants, Cancer Biology, Tumor Biology +16

Blocking the Protease-Activated Receptor 1-4 Heterodimer in Platelet-Mediated Thrombosis

Andrew J. Leger, Suzanne L. Jacques, Jehangir Badar et al. · Circulation · 2006 · 215 citations

Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound

Lorna H. Mitchell, Allison E. Drew, Scott Ribich et al. · ACS Medicinal Chemistry Letters · 2015 · 134 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +18