Joe C. Wu

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

K.S. Gajiwala, Joe C. Wu, James G. Christensen et al. · Proceedings of the National Academy of Sciences · 2009 · 380 citations · Full text

Kit Kinase Mutants, Cancer Biology, Tumor Biology +16

Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry

Hui‐Min Zhang, Xiu Yu, Michael J. Greig et al. · Protein Science · 2010 · 28 citations · Full text

Drug Target, Molecular Biology, Resistance Mechanism +19

Enhanced selectivity profile of pyrazole-urea based DFG-out p38α inhibitors

Hu Liu, Cyrille Kuhn, Frédéric Féru et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 11 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +9

The Design, Synthesis and Potential Utility of Fluorescence Probes that Target DFG‐out Conformation of p38α for High Throughput Screening Binding Assay

Haile Tecle, Frédéric Féru, Hu Liu et al. · Chemical Biology & Drug Design · 2009 · 11 citations · Full text