Frédéric Féru

Exploring Targeted Degradation Strategy for Oncogenic KRASG12C

Mei Zeng, Yuan Xiong, Nozhat Safaee et al. · Cell chemical biology · 2019 · 275 citations · Full text

Medicine, Molecular Biology, Molecular Genetics +11

Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C

Mei Zeng, Jia Lu, Lianbo Li et al. · Cell chemical biology · 2017 · 137 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Research Article: Selectivity‐determining Residues in Plk1

Michael Kothe, Darcy Kohls, Simon Low et al. · Chemical Biology & Drug Design · 2007 · 128 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +13

Synthesis, Structure−Activity Relationships, and Pharmacological Profile of 9-Amino-4-oxo-1-phenyl-3,4,6,7-tetrahydro[1,4]diazepino[6,7,1-<i>h</i><i>i</i>]indoles:  Discovery of Potent, Selective Phosphodiesterase Type 4 Inhibitors

Catherine Burnouf, Eric Auclair, Nadine Avenel et al. · Journal of Medicinal Chemistry · 2000 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis and structure–activity relationships of 4-oxo-1-phenyl-3,4,6,7-tetrahydro-[1,4]diazepino[6,7,1-hi]indoles: novel PDE4 inhibitors

Yves Pascal, Charles R. Andrianjara, Eric Auclair et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14