Lorna H. Mitchell - Concepedia

Author

Lorna H. Mitchell

Pfizer (United States)

Also Known As

L. H. MITCHELL, L. H. Mitchell, L. Mitchell, Lorna H. Mitchell, Lorna Mitchell, Mitchell, L.H., Mitchell, Lorna

Publications

1.3K

Citations

H-Index

Concepts

All Affiliations

Pfizer (United States)Epizyme (United States)GlaxoSmithKline (United States)

About

Lorna H. Mitchell is an author at Pfizer (United States) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	11	11	826
2	Natural Sciences	4	4	257
3	Engineering	2	2	67
4	Public Health	1	1	12
5	Allergy	1	1	119

Lorna H. Mitchell

Publications

1.2K

Citations

H-Index

Page 1

	Year	Citations
Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss Andrew Fedoriw, Satyajit Rajapurkar, Shane W. O’Brien, Cancer Cell Cancer ResearchMtap LossMedicinePharmacologyCell Death	2019	333
Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound Lorna H. Mitchell, Allison E. Drew, Scott Ribich, ACS Medicinal Chemistry Letters Drug TargetPharmacotherapyChemical BiologyPharmaceutical ChemistryPrmt6 Overexpression	2015	134
Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma Allison E. Drew, Oscar Moradei, Suzanne L. Jacques, Scientific Reports	2017	131
Identification of Cells Expressing IL-17A and IL-17F in the Lungs of Patients With COPD Amanda Eustace, Lucy J.C. Smyth, Lorna H. Mitchell, CHEST Journal InflammationAllergyInflammatory Lung DiseaseLung InflammationAdvanced Lung Disease	2010	119
4-Phenylpyrrolo[3,4-<i>c</i>]carbazole-1,3(2<i>H</i>,6<i>H</i>)-dione Inhibitors of the Checkpoint Kinase Wee1. Structure−Activity Relationships for Chromophore Modification and Phenyl Ring Substitution Brian D. Palmer, Andrew M. Thompson, R J Booth, Journal of Medicinal Chemistry	2006	107
Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor Lorna H. Mitchell, P. Ann Boriack‐Sjodin, Sherri Smith, ACS Medicinal Chemistry Letters Pharmaceutical ScienceChemoprevention StrategyCancer BiologySmyd3 InhibitorsPharmaceutical Chemistry	2015	83
Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation Michael J. Thomenius, Jennifer Totman, Darren M. Harvey, PLoS ONE Small Molecule InhibitorsEngineeringMolecular BiologySpecific Target MacromoleculesTumor Biology	2018	55
An Enantioselective Total Synthesis of (+)- and (−)-Saudin. Determination of the Absolute Configuration Robert K. Boeckman, Marı́a del Rosario Rico Ferreira, Lorna H. Mitchell, Journal of the American Chemical Society	2001	44
A homologous enolate Truce–Smiles rearrangement Lorna H. Mitchell, Nicole C. Barvian Tetrahedron Letters PeacemakingCultural History	2004	36
A Practical Buchwald−Hartwig Amination of 2-Bromopyridines with Volatile Amines Jie Jack Li, Zhi Wang, Lorna H. Mitchell The Journal of Organic Chemistry	2007	30

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