Lorna H. Mitchell

Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss

Andrew Fedoriw, Satyajit Rajapurkar, Shane W. O’Brien et al. · Cancer Cell · 2019 · 333 citations · Full text

Cancer Research, Mtap Loss, Medicine +10

Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound

Lorna H. Mitchell, Allison E. Drew, Scott Ribich et al. · ACS Medicinal Chemistry Letters · 2015 · 134 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +18

Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma

Allison E. Drew, Oscar Moradei, Suzanne L. Jacques et al. · Scientific Reports · 2017 · 131 citations · Full text

Identification of Cells Expressing IL-17A and IL-17F in the Lungs of Patients With COPD

Amanda Eustace, Lucy J.C. Smyth, Lorna H. Mitchell et al. · CHEST Journal · 2010 · 119 citations · Full text

Inflammation, Allergy, Inflammatory Lung Disease +8

4-Phenylpyrrolo[3,4-<i>c</i>]carbazole-1,3(2<i>H</i>,6<i>H</i>)-dione Inhibitors of the Checkpoint Kinase Wee1. Structure−Activity Relationships for Chromophore Modification and Phenyl Ring Substitution

Brian D. Palmer, Andrew M. Thompson, R J Booth et al. · Journal of Medicinal Chemistry · 2006 · 107 citations · Full text