William Day

CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial

Shaun Cordoba, Shimobi Onuoha, Simon Thomas et al. · Nature Medicine · 2021 · 272 citations · Full text

Medicine, Hematology, Oncology +17

Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress

Richard Burt, Aditi Dey, Sarah Aref et al. · Blood · 2019 · 243 citations · Full text

Life Sciences, Cell Biology, Oncology +16

Antitumor activity without on-target off-tumor toxicity of GD2–chimeric antigen receptor T cells in patients with neuroblastoma

Karin Straathof, Barry Flutter, Rebecca Wallace et al. · Science Translational Medicine · 2020 · 205 citations

Life Sciences, Immunology, Oncology +17

Mechanisms of PD-L1/PD-1–mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the Eµ-TCL1 CLL mouse model

Fabienne McClanahan, John C. Riches, Shaun Miller et al. · Blood · 2015 · 110 citations · Full text

Life Sciences, Cancer Biology, Immunology +17

The T cell differentiation landscape is shaped by tumour mutations in lung cancer

Ehsan Ghorani, James L. Reading, Jake Y. Henry et al. · Nature Cancer · 2020 · 102 citations · Full text

Life Sciences, Cancer Biology, Oncology +15