Autolus (United Kingdom)

Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR

Sara Ghorashian, Anne Marijn Kramer, Shimobi Onuoha et al. · Nature Medicine · 2019 · 613 citations

Cell Therapy, Prolonged Persistence, Autoimmune Disease +9

Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies

Paul Maciocia, Patrycja Wawrzyniecka, Brian Philip et al. · Nature Medicine · 2017 · 276 citations

Tumor Immunology, Cancer Immunosurveillance, Immunology +7

CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial

Shaun Cordoba, Shimobi Onuoha, Simon Thomas et al. · Nature Medicine · 2021 · 260 citations · Full text

An APRIL-based chimeric antigen receptor for dual targeting of BCMA and TACI in multiple myeloma

Lydia Lee, Benjamin Draper, Neil Chaplin et al. · Blood · 2017 · 166 citations · Full text

Durable Responses and Low Toxicity After Fast Off-Rate CD19 Chimeric Antigen Receptor-T Therapy in Adults With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia

Claire Roddie, Juliana Dias, Maeve O’Reilly et al. · Journal of Clinical Oncology · 2021 · 133 citations · Full text