Sara Ghorashian

Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells

Waseem Qasim, Hong Zhan, Sujith Samarasinghe et al. · Science Translational Medicine · 2017 · 888 citations · Full text

Life Sciences, Immunology, Oncology +17

Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR

Sara Ghorashian, Anne Marijn Kramer, Shimobi Onuoha et al. · Nature Medicine · 2019 · 644 citations · Full text

Life Sciences, Immunology, Pediatrics +16

Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial

Gérardo Priotto, S Kasparian, Wilfried Mutombo et al. · The Lancet · 2009 · 532 citations

Veterinary Medicine, Infectious Diseases, Pharmacology +12

CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial

Shaun Cordoba, Shimobi Onuoha, Simon Thomas et al. · Nature Medicine · 2021 · 272 citations · Full text

Medicine, Hematology, Oncology +17

Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia

Giorgio Ottaviano, Christos Georgiadis, Soragia Athina Gkazi et al. · Science Translational Medicine · 2022 · 184 citations · Full text

Life Sciences, Biotechnology, Immunology +17