John C. Riches

Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma

Abasi Ene–Obong, Andrew Clear, Jennifer Watt et al. · Gastroenterology · 2013 · 566 citations · Full text

Medicine, Cell Biology, Oncology +11

T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production

John C. Riches, Jeffrey K. Davies, Fabienne McClanahan et al. · Blood · 2012 · 527 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Single-cell analysis of human B cell maturation predicts how antibody class switching shapes selection dynamics

Hamish W. King, Nara Orban, John C. Riches et al. · Science Immunology · 2021 · 278 citations

Life Sciences, Cell Biology, Immunology +15

Mechanisms of PD-L1/PD-1–mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the Eµ-TCL1 CLL mouse model

Fabienne McClanahan, John C. Riches, Shaun Miller et al. · Blood · 2015 · 110 citations · Full text

Life Sciences, Cancer Biology, Immunology +17

Trisomy 12 chronic lymphocytic leukemia cells exhibit upregulation of integrin signaling that is modulated by NOTCH1 mutations

John C. Riches, Conor J. O’Donovan, Sarah J. Kingdon et al. · Blood · 2014 · 70 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11