Jake Y. Henry

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

Nicholas McGranahan, Andrew J.S. Furness, Rachel Rosenthal et al. · Science · 2016 · 3.1K citations · Full text

Life Sciences, Immunology, Oncology +17

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma

Tyler R. Simpson, Fubin Li, Welby Montalvo-Ortiz et al. · The Journal of Experimental Medicine · 2013 · 1.5K citations

Medicine, Immunology, Oncology +17

Neoantigen-directed immune escape in lung cancer evolution

Rachel Rosenthal, Elizabeth Larose Cadieux, Roberto Salgado et al. · Nature · 2019 · 976 citations · Full text

Medicine, Immunology, Oncology +14

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies

Frederick Arce Vargas, Andrew J.S. Furness, Kevin Litchfield et al. · Cancer Cell · 2018 · 585 citations · Full text

Medicine, Immunology, Oncology +17

Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors

Frederick Arce Vargas, Andrew J.S. Furness, Isabelle Solomon et al. · Immunity · 2017 · 430 citations · Full text

Medicine, Immunology, Oncology +17