Jimmy Jacob

The estrogen receptor-α-induced microRNA signature regulates itself and its transcriptional response

Leandro Castellano, Georgios Giamas, Jimmy Jacob et al. · Proceedings of the National Academy of Sciences · 2009 · 325 citations · Full text

Suppression of the Deubiquitinating Enzyme USP5 Causes the Accumulation of Unanchored Polyubiquitin and the Activation of p53

Saurabh Dayal, Alison Sparks, Jimmy Jacob et al. · Journal of Biological Chemistry · 2008 · 200 citations · Full text

Transcriptional Regulation, Unanchored Polyubiquitin, Ubiquitinated P53 +15

MicroRNAs Cooperatively Inhibit a Network of Tumor Suppressor Genes to Promote Pancreatic Tumor Growth and Progression

Adam E. Frampton, Leandro Castellano, Teresa Colombo et al. · Gastroenterology · 2013 · 168 citations

Pancreatic Cancer, Medicine, Pathology +8

MicroRNAs Targeting Oncogenes Are Down-Regulated in Pancreatic Malignant Transformation from Benign Tumors

Long R. Jiao, Adam E. Frampton, Jimmy Jacob et al. · PLoS ONE · 2012 · 138 citations · Full text

Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer

Georgios Giamas, Aleksandra Filipović, Jimmy Jacob et al. · Nature Medicine · 2011 · 133 citations

Breast Oncology, Signaling Pathway, Receptor Tyrosine Kinase +8