Arno L. Greenleaf

A Novel Domain in Set2 Mediates RNA Polymerase II Interaction and Couples Histone H3 K36 Methylation with Transcript Elongation

Kelby O. Kizer, Hemali Phatnani, Yoichiro Shibata et al. · Molecular and Cellular Biology · 2005 · 511 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

Bartlomiej Bartkowiak, Pengda Liu, Hemali Phatnani et al. · Genes & Development · 2010 · 401 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors

Tinghu Zhang, Nicholas Kwiatkowski, Sarah E. Dixon-Clarke et al. · Nature Chemical Biology · 2016 · 372 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +16

Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation

Thomas O’Brien, S. E. Hardin, Arno L. Greenleaf et al. · Nature · 1994 · 327 citations

Life Sciences, Biochemistry, Molecular Biology +14

CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation

Małgorzata Krajewska, Ruben Dries, Andrew V. Grassetti et al. · Nature Communications · 2019 · 270 citations · Full text

Life Sciences, Genetics, Molecular Biology +13