Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+

Chee-Huat Linus Eng, Michael J. Lawson, Qian Zhu, +8

Nature

Tissue ImagingEngineeringRna Seqfish+Biomedical ImagingCell Biology +2

Giotto: a toolbox for integrative analysis and visualization of spatial expression data

Ruben Dries, Qian Zhu, Rui Dong, +11

Genome biology

CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation

Jiehui Deng, Eric S. Wang, Russell W. Jenkins, +43

Cancer Discovery

Identification of spatially associated subpopulations by combining scRNAseq and sequential fluorescence in situ hybridization data

Qian Zhu, Sheel Shah, Ruben Dries, +2

Nature Biotechnology

BiologyGenetic DiversityHybridisationMedicineGenetics +9

CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation

Małgorzata Krajewska, Ruben Dries, Andrew V. Grassetti, +17

Nature Communications

CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer

Hua Zhang, Camilla L. Christensen, Ruben Dries, +45

Cancer Cell

Cancer ImmunosurveillanceMedicineImmunologyTumor ImmunityImmune Checkpoint Inhibitor +5

Genomic and Functional Fidelity of Small Cell Lung Cancer Patient-Derived Xenografts

Benjamin J. Drapkin, Julie George, Camilla L. Christensen, +30

Cancer Discovery

Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade

Esra A. Akbay, Shohei Koyama, Yan Liu, +21

Journal of Thoracic Oncology

Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non–Small Cell Lung Cancer

Dennis O. Adeegbe, Yan Liu, Patrick H. Lizotte, +22

Cancer Discovery

BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells

David Debruyne, Ruben Dries, Satyaki Sengupta, +15

Nature

ChromatinChromatin Regulatory InteractionsMedicineTumor SuppressorCancer Biology +3