L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans.

Mark A. Creager, Stuart Gallagher, Xavier Girerd, +3

Journal of Clinical Investigation

Cardiovascular DiseaseNitric OxideMedicinePhysiologyHypercholesterolemic Humans +12

The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transfer.

Masatoshi Nakajima, Howard G. Hutchinson, Masahiko Fujinaga, +6

Proceedings of the National Academy of Sciences

Growth EffectsCellular PhysiologyMolecular PharmacologyType 1Angiogenesis +21

Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation.

Heribert Schunkert, V J Dzau, Shiow‐Shih Tang, +3

Journal of Clinical Investigation

HypertensionHeart FailureCardiovascular PharmacologyCardiovascular FunctionCardiac Ace +17

Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II.

Hiroaki Itoh, Masashi Mukoyama, R E Pratt, +2

Journal of Clinical Investigation

HypertensionCell ProliferationAng IiAntisense OligomersCellular Physiology +14

High-Throughput Genotyping with Single Nucleotide Polymorphisms

Koustubh Ranade, Mau-Song Chang, Chih‐Tai Ting, +12

Genome Research

Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction.

M. Paul, J. Wagner, V J Dzau

Journal of Clinical Investigation

HypertensionTissue RasPolymerase Chain ReactionRenal FunctionQuantitative Analysis +14

Intracellular Trafficking of Angiotensin II and its AT₁and AT₂Receptors: Evidence for Selective Sorting of Receptor and Ligand

Lutz Hein, Lorenz Meinel, Richard E. Pratt, +2

Molecular Endocrinology

ImmunologyAng IiCellular PhysiologyMolecular PharmacologySteady State +17

Endothelial renin-angiotensin pathway: evidence for intracellular synthesis and secretion of angiotensins.

Imre Kifor, V J Dzau

Circulation Research

Endothelial Cell PathobiologyInflammationAnimal PhysiologyAngiogenesisAngiotensin Ii +12

Identification of renin and angiotensinogen messenger RNA sequences in mouse and rat brains.

V J Dzau, J R Ingelfinger, Richard E. Pratt, +1

Hypertension

Molecular NeuroscienceMolecular PhysiologyEngineeringGeneticsRna Biology +13

Sodium regulation of angiotensinogen mRNA expression in rat kidney cortex and medulla.

J R Ingelfinger, Richard E. Pratt, Kristin Ellison, +1

Journal of Clinical Investigation

HypertensionRenal InflammationRenal FunctionSodium RegulationPrang 3 +17