The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells

Kaoru Mitsui, Yoshimi Tokuzawa, Hiroaki Itoh, +6

Cell

Knockout MouseHomeoprotein NanogInduced Pluripotent Stem CellDevelopmental BiologyMouse Epiblast +6

Peroral endoscopic myotomy (POEM) for esophageal achalasia

Haruhiro Inoue, Hironobu Minami, Yasutoshi Kobayashi, +7

Endoscopy

Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload.

Osamu Nakagawa, Yoshihiro Ogawa, Hiroaki Itoh, +6

Journal of Clinical Investigation

Cardiac MuscleHeart FailureCardiac HormoneCardiovascular FunctionBnp Gene Expression +15

Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II.

Hiroaki Itoh, Masashi Mukoyama, R E Pratt, +2

Journal of Clinical Investigation

HypertensionCell ProliferationAng IiAntisense OligomersCellular Physiology +14

Atrial natriuretic polypeptide inhibits hypertrophy of vascular smooth muscle cells.

Hiroaki Itoh, Richard E. Pratt, Victor J. Dzau

Journal of Clinical Investigation

HypertensionCardiovascular PharmacologyCardiovascular FunctionCellular PhysiologyAtherosclerosis +14

Augmented Placental Production of Leptin in Preeclampsia: Possible Involvement of Placental Hypoxia¹

Hiroko Mise, Norimasa Sagawa, Tsunekazu Matsumoto, +8

The Journal of Clinical Endocrinology & Metabolism

Pregnancy DisordersGynecologyLeptin ProductionLeptin SecretionEmbryology +18

Neural substrates of irony comprehension: A functional MRI study

Midori Shibata, Akira Toyomura, Hiroaki Itoh, +1

Brain Research

Cognitive ScienceExperimental PragmaticNeurolinguisticsSemantic ProcessingAffective Neuroscience +6

Dietary cadmium intake and breast cancer risk in Japanese women: A case–control study

Hiroaki Itoh, Motoki Iwasaki, Norie Sawada, +8

International Journal of Hygiene and Environmental Health

NutritionNutritional EpidemiologyCancer EpidemiologyBreast Cancer RiskDietary Exposure +13

Peroral endoscopic myotomy and fundoplication: a novel NOTES procedure

Haruhiro Inoue, Akiko Ueno, Yuto Shimamura, +10

Endoscopy

Accelerated puberty and late-onset hypothalamic hypogonadism in female transgenic skinny mice overexpressing leptin

Shigeo Yura, Yoshihiro Ogawa, Norimasa Sagawa, +6

Journal of Clinical Investigation

FertilityLate-onset Hypothalamic HypogonadismNeuroendocrinologyFemale Reproductive FunctionReproductive Biology +17