Janet Dell

Discovery of a 1<i>H</i>-Benzoimidazol-2-yl)-1<i>H</i>-pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity

Mark D. Wittman, Joan M. Carboni, Ricardo M. Attar et al. · Journal of Medicinal Chemistry · 2005 · 134 citations · Full text

Pharmacotherapy, Insulin Receptor, Insulin Signaling +21

Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development.

David K. Bol, R. Rowley, Ching-Ping Ho et al. · PubMed · 2002 · 113 citations

Cyclooxygenase-2 Overexpression, Dermatology, Transgenic Mice +16

Adenovirus-mediated p53 gene therapy has greater efficacy when combined with chemotherapy against human head and neck, ovarian, prostate, and breast cancer

Maya Gurnani, Philip Lipari, Janet Dell et al. · Cancer Chemotherapy and Pharmacology · 1999 · 109 citations

Greater Efficacy, Medicine, Pathology +9

Structure−Activity Relationship of 3-Substituted <i>N</i>-(Pyridinylacetyl)-4- (8-chloro-5,6-dihydro-11<i>H</i>-benzo[5,6]cyclohepta[1,2-<i>b</i>]pyridin-11-ylidene)- piperidine Inhibitors of Farnesyl-Protein Transferase:  Design and Synthesis of in Vivo Active Antitumor Compounds

F. George Njoroge, Bancha Vibulbhan, Dinananth F. Rane et al. · Journal of Medicinal Chemistry · 1997 · 52 citations · Full text

Analogue 38, Analogues 19, Pharmacotherapy +16

Thyroid hormone suppression of β-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events

Madesh Belakavadi, Janet Dell, Gary J. Grover et al. · Molecular and Cellular Endocrinology · 2011 · 49 citations

Brain Development, Medicine, Genetics +10