R. Rowley

Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement.

Sandra J. Saouaf, S Mahajan, R. Rowley et al. · Proceedings of the National Academy of Sciences · 1994 · 247 citations

Life Sciences, Biochemistry, Immunology +17

Checkpoint controls in Schizosaccharomyces pombe: rad1.

R. Rowley, Suresh Subramani, Paul G. Young · The EMBO Journal · 1992 · 218 citations · Full text

Life Sciences, Genetics, Molecular Biology +11

Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase.

Peter A. Kiener, Bruce Rankin, Anne L. Burkhardt et al. · Journal of Biological Chemistry · 1993 · 196 citations · Full text

Life Sciences, Cell Biology, Immunology +17

The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling.

David H. Chu, Hergen Spits, Jean‐François Peyron et al. · The EMBO Journal · 1996 · 128 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Discovery and SAR of Novel 2,3‐Dihydroimidazo[1,2‐<i>c</i>]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80‐6946)

William J. Scott, Martin Hentemann, R. Rowley et al. · ChemMedChem · 2016 · 117 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13