Martin Hentemann

BAY 80-6946 Is a Highly Selective Intravenous PI3K Inhibitor with Potent p110α and p110δ Activities in Tumor Cell Lines and Xenograft Models

Ningshu Liu, Bruce R. Rowley, Cathy Bull et al. · Molecular Cancer Therapeutics · 2013 · 251 citations

Molecular Pharmacology, Tumor Biology, Pi3k Inhibitors +15

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer

Matthew J. LaMarche, Michael Acker, Andreea Argintaru et al. · Journal of Medicinal Chemistry · 2020 · 207 citations · Full text

Discovery and SAR of Novel 2,3‐Dihydroimidazo[1,2‐<i>c</i>]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80‐6946)

William J. Scott, Martin Hentemann, R. Rowley et al. · ChemMedChem · 2016 · 111 citations · Full text

Antibacterial Inhibitors of Gram-Positive Thymidylate Kinase: Structure–Activity Relationships and Chiral Preference of a New Hydrophobic Binding Region

Sameer Kawatkar, Thomas A. Keating, N.B. Olivier et al. · Journal of Medicinal Chemistry · 2014 · 61 citations

Antibiotic Adjuvant, Molecular Biology, Peptide Science +23

Thermal Intermolecular Hetero Diels–Alder Cycloadditions of Aldehydes and Imines viao-Quinone Dimethides

Martin Hentemann, John G. Allen, Samuel J. Danishefsky · Angewandte Chemie International Edition · 2000 · 54 citations

Chemical Engineering, Engineering, Heterocyclic +13