Bancha Vibulbhan

Discovery of (1 <i>R</i> ,5 <i>S</i> )- <i>N</i> -[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2( <i>S</i> )-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2( <i>S</i> )-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor:  A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection

Srikanth Venkatraman, Stéphane Bogen, Ashok Arasappan et al. · Journal of Medicinal Chemistry · 2006 · 278 citations · Full text

Ras oncoprotein inhibitors: The discovery of potent, ras nucleotide exchange inhibitors and the structural determination of a drug-protein complex

Arthur G. Taveras, Stacy Remiszewski, Ronald J. Doll et al. · Bioorganic & Medicinal Chemistry · 1997 · 121 citations

Molecular Docking, Drug Target, Biochemistry +10

(+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5<i>H</i>-benzo[5,6]cyclohepta[1,2-<i>b</i>]- pyridin-11(<i>R</i>)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamide (SCH-66336):  A Very Potent Farnesyl Protein Transferase Inhibitor as a Novel Antitumor Agent

F. George Njoroge, Arthur G. Taveras, Joseph Kelly et al. · Journal of Medicinal Chemistry · 1998 · 97 citations · Full text

Bioorganic Chemistry, Pharmacotherapy, Pharmaceutical Chemistry +18

Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor

Ashok Arasappan, Frank Bennett, Stéphane Bogen et al. · ACS Medicinal Chemistry Letters · 2010 · 95 citations · Full text

Protease Inhibitors, Medicinal Chemistry, Synthetic Virology +11

Tricyclic Farnesyl Protein Transferase Inhibitors:  Crystallographic and Calorimetric Studies of Structure−Activity Relationships

Corey L. Strickland, Patricia C Weber, William T. Windsor et al. · Journal of Medicinal Chemistry · 1999 · 88 citations · Full text

Amide Carbonyl, Molecular Biology, Complex Formation +17