Stacy Remiszewski

Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice.

Ming Liu, Matthew Bryant, Jianping Chen et al. · PubMed · 1998 · 309 citations

Sch 66336, Chemoprevention Strategy, Farnesyl Protein Transferase +15

Psammaplins from the Sponge <i>Pseudoceratina </i><i>p</i><i>urpurea:</i> Inhibition of Both Histone Deacetylase and DNA Methyltransferase

Ivette C. Piña, Jeffrey T. Gautschi, Gui-Yang-Sheng Wang et al. · The Journal of Organic Chemistry · 2003 · 307 citations

Epigenetic Change, Molecular Biology, Dna Methyltransferase +22

NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma

Laurence Catley, Ellen Weisberg, Yu-Tzu Tai et al. · Blood · 2003 · 219 citations · Full text

Selective Growth Inhibition of Tumor Cells by a Novel Histone Deacetylase Inhibitor, NVP-LAQ824

Peter Atadja, Lin Gao, Paul Kwon et al. · Cancer Research · 2004 · 134 citations

Histone Modifications, Histone Deacetylase Inhibitor, Tumor Cells +17

<i>N</i>-Hydroxy-3-phenyl-2-propenamides as Novel Inhibitors of Human Histone Deacetylase with in Vivo Antitumor Activity:  Discovery of (2<i>E</i>)-<i>N</i>-Hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1<i>H</i>-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824)

Stacy Remiszewski, Lidia Sambucetti, Kenneth W. Bair et al. · Journal of Medicinal Chemistry · 2003 · 129 citations · Full text

Pathology, Pharmacotherapy, Pharmaceutical Chemistry +17