Paul Kwon

Histone Deacetylase Inhibition Selectively Alters the Activity and Expression of Cell Cycle Proteins Leading to Specific Chromatin Acetylation and Antiproliferative Effects

Lidia Sambucetti, Denise Fischer, Sonya Zabludoff et al. · Journal of Biological Chemistry · 1999 · 393 citations · Full text

Life Sciences, Cancer Biology, Oncology +10

Selective Growth Inhibition of Tumor Cells by a Novel Histone Deacetylase Inhibitor, NVP-LAQ824

Peter Atadja, Lin Gao, Paul Kwon et al. · Cancer Research · 2004 · 134 citations

Medicine, Cell Biology, Oncology +11

<i>N</i>-Hydroxy-3-phenyl-2-propenamides as Novel Inhibitors of Human Histone Deacetylase with in Vivo Antitumor Activity:  Discovery of (2<i>E</i>)-<i>N</i>-Hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1<i>H</i>-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824)

Stacy Remiszewski, Lidia Sambucetti, Kenneth W. Bair et al. · Journal of Medicinal Chemistry · 2003 · 129 citations · Full text

Medicine, Oncology, Pharmacology +13

Inhibitors of Human Histone Deacetylase:  Synthesis and Enzyme and Cellular Activity of Straight Chain Hydroxamates

Stacy Remiszewski, Lidia Sambucetti, Peter Atadja et al. · Journal of Medicinal Chemistry · 2002 · 114 citations · Full text

Medicine, Oncology, Pharmacology +14

Activity of deacetylase inhibitor panobinostat (LBH589) in cutaneous T‐cell lymphoma models: Defining molecular mechanisms of resistance

Wenlin Shao, Joseph D. Growney, Yun Feng et al. · International Journal of Cancer · 2010 · 90 citations · Full text

Medicine, Oncology, Pharmacology +13