BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression

Aldo M. Roccaro, Antonio Sacco, Patricia Maiso, +10

Journal of Clinical Investigation

MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma

Masahisa Jinushi, Matthew W. Vanneman, Nikhil C. Munshi, +7

Proceedings of the National Academy of Sciences

NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma

Laurence Catley, Ellen Weisberg, Yu-Tzu Tai, +12

Blood

Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein.

Masaharu Akiyama, Teru Hideshima, Toshiaki Hayashi, +7

PubMed

Transcriptional RegulationSignaling PathwayCell RegulationMedicineTelomerase Activity +11

Targeting the β-catenin/TCF transcriptional complex in the treatment of multiple myeloma

Kumar Sukhdeo, Mala Mani, Yunyu Zhang, +10

Proceedings of the National Academy of Sciences

Hematological MalignancyTumor BiologySignaling PathwayMedicineImmunology +13

SHP2 Mediates the Protective Effect of Interleukin-6 against Dexamethasone-induced Apoptosis in Multiple Myeloma Cells

Dharminder Chauhan, Pramod S. Pandey, Teru Hideshima, +9

Journal of Biological Chemistry

ApoptosisImmunologyCell DeathImmunologic MechanismInflammation +18

Cytokines modulate telomerase activity in a human multiple myeloma cell line.

Masaharu Akiyama, Teru Hideshima, Toshiaki Hayashi, +7

PubMed

Hematological MalignancyCell RegulationMm Cell LinesMedicineImmunology +8

Caveolin-1 Is Required for Vascular Endothelial Growth Factor-Triggered Multiple Myeloma Cell Migration and Is Targeted by Bortezomib

Klaus Podar, Reshma Shringarpure, Yu-Tzu Tai, +7

Cancer Research

Effects of oligonucleotide N3'-->P5' thio-phosphoramidate (GRN163) targeting telomerase RNA in human multiple myeloma cells.

Masaharu Akiyama, Teru Hideshima, Masood A. Shammas, +7

PubMed

Molecular BiologyCell CycleTelomerase RnaCancer BiologyTumor Biology +17

Generation of Antitumor Invariant Natural Killer T Cell Lines in Multiple Myeloma and Promotion of Their Functions via Lenalidomide: A Strategy for Immunotherapy

Weihua Song, Hans van Vliet, Yu-Tzu Tai, +9

Clinical Cancer Research