Dinananth F. Rane

(+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5<i>H</i>-benzo[5,6]cyclohepta[1,2-<i>b</i>]- pyridin-11(<i>R</i>)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamide (SCH-66336):  A Very Potent Farnesyl Protein Transferase Inhibitor as a Novel Antitumor Agent

F. George Njoroge, Arthur G. Taveras, Joseph Kelly et al. · Journal of Medicinal Chemistry · 1998 · 97 citations · Full text

Bioorganic Chemistry, Pharmacotherapy, Pharmaceutical Chemistry +18

Structure−Activity Relationship of 3-Substituted <i>N</i>-(Pyridinylacetyl)-4- (8-chloro-5,6-dihydro-11<i>H</i>-benzo[5,6]cyclohepta[1,2-<i>b</i>]pyridin-11-ylidene)- piperidine Inhibitors of Farnesyl-Protein Transferase:  Design and Synthesis of in Vivo Active Antitumor Compounds

F. George Njoroge, Bancha Vibulbhan, Dinananth F. Rane et al. · Journal of Medicinal Chemistry · 1997 · 52 citations · Full text

Analogue 38, Analogues 19, Pharmacotherapy +16

Identification of Novel Farnesyl Protein Transferase Inhibitors Using Three-Dimensional Database Searching Methods

James J. Kaminski, Dinananth F. Rane, Mark E. Snow et al. · Journal of Medicinal Chemistry · 1997 · 48 citations · Full text

Isobenzofurans as conformationally constrained miconazole analogs with improved antifungal potency

Raymond G. Lovey, Arthur J. Elliott, James J. Kaminski et al. · Journal of Medicinal Chemistry · 1992 · 32 citations