Scott A. Bolton

Synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors

James Sutton, Scott A. Bolton, Karen S. Hartl et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 67 citations · Full text

Medicinal Chemistry, Medicine, Pharmacological Agent +5

Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors

James Sutton, Scott A. Bolton, Malcolm E. Davis et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 63 citations · Full text

Medicinal Chemistry, Solid-phase Synthesis, Medicine +5

Synthesis of potent and highly selective inhibitors of human tryptase

William A. Slusarchyk, Scott A. Bolton, Karen S. Hartl et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 49 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +9

Discovery of an Oxybenzylglycine Based Peroxisome Proliferator Activated Receptor α Selective Agonist 2-((3-((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic Acid (BMS-687453)

Jun Li, Lawrence J. Kennedy, Yan Shi et al. · Journal of Medicinal Chemistry · 2010 · 40 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Crystal Structure +14

Identification and Initial Structure−Activity Relationships of a Novel Class of Nonpeptide Inhibitors of Blood Coagulation Factor Xa

Scott I. Klein, Mark Czekaj, Charles J. Gardner et al. · Journal of Medicinal Chemistry · 1998 · 39 citations · Full text

Vitro Potency, Pharmacotherapy, Initial Structure−activity Relationships +20