Concepedia

Synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors

James Sutton, Scott A. Bolton, Karen S. Hartl, Ming‐Hsing Huang, G. A. JACOBS, Wei Meng, Martin L. Ogletree, Zulan Pi, William A. Schumacher, Steven M. Seiler,

Bioorganic & Medicinal Chemistry Letters · 2002 · 68 citations · 5 references

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References

5

Azetidin-2-one derivatives as inhibitors of thrombin

William T. Han, Ashok K. Trehan, J. J. Wright et al. · Bioorganic & Medicinal Chemistry · 1995 · 155 citations

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Stereospecific synthesis of dealanylalahopcin

Jack E. Baldwin, Robert M. Adlington, David W. Gollins et al. · Tetrahedron · 1990 · 74 citations

, , +7

1,2-Benzisothiazol-3-one 1,1-Dioxide Inhibitors of Human Mast Cell Tryptase

Keith D. Combrink, H. Belgin Gülgeze, Nicholas A. Meanwell et al. · Journal of Medicinal Chemistry · 1998 · 54 citations · Full text

, , +17

Mast cell tryptase and asthma

M-Q. Zhang, H. Timmerman · Mediators of Inflammation · 1997 · 22 citations · Full text

, , +16

Emerging therapeutic targets in asthma: the rationale for mast cell tryptase inhibition

Kyle Elrod, Robert P. Numerof · Emerging Therapeutic Targets · 1999 · 13 citations

, , +14