Zulan Pi

Conformationally Constrained <i>ortho-</i>Anilino Diaryl Ureas: Discovery of 1-(2-(1′-Neopentylspiro[indoline-3,4′-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a Potent, Selective, and Bioavailable P2Y₁ Antagonist

Jennifer X. Qiao, Tammy C. Wang, Réjean Ruel et al. · Journal of Medicinal Chemistry · 2013 · 70 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors

James Sutton, Scott A. Bolton, Karen S. Hartl et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Discovery of Potent and Muscle Selective Androgen Receptor Modulators through Scaffold Modifications

James J. Li, James Sutton, Alexandra A. Nirschl et al. · Journal of Medicinal Chemistry · 2007 · 56 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

1,2-Benzisothiazol-3-one 1,1-Dioxide Inhibitors of Human Mast Cell Tryptase

Keith D. Combrink, H. Belgin Gülgeze, Nicholas A. Meanwell et al. · Journal of Medicinal Chemistry · 1998 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis of potent and highly selective inhibitors of human tryptase

William A. Slusarchyk, Scott A. Bolton, Karen S. Hartl et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7