Alexandra A. Nirschl

Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Wei Meng, Bruce A. Ellsworth, Alexandra A. Nirschl et al. · Journal of Medicinal Chemistry · 2008 · 612 citations · Full text

Metabolic Syndrome, Diabetes Management, Biochemistry +10

Discovery of Potent and Muscle Selective Androgen Receptor Modulators through Scaffold Modifications

James J. Li, James Sutton, Alexandra A. Nirschl et al. · Journal of Medicinal Chemistry · 2007 · 56 citations · Full text

Androgen Receptor, Pharmacotherapy, Medicinal Chemistry +19

<i>N</i>-Aryl-oxazolidin-2-imine Muscle Selective Androgen Receptor Modulators Enhance Potency through Pharmacophore Reorientation

Alexandra A. Nirschl, Yan Zou, Stanley R. Krystek et al. · Journal of Medicinal Chemistry · 2009 · 29 citations · Full text

Pharmaceutical Science, Gut Ph, Pharmacotherapy +16

Synthesis and SAR of tetrahydropyrrolo[1,2-b][1,2,5]thiadiazol-2(3H)-one 1,1-dioxide analogues as highly potent selective androgen receptor modulators

Mark C. Manfredi, Yingzhi Bi, Alexandra A. Nirschl et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 23 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Diversity Oriented Synthesis +7