Scott I. Klein

Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors

S. Maignan, J.P. Guilloteau, Stéphanie Pouzieux et al. · Journal of Medicinal Chemistry · 2000 · 139 citations · Full text

X-ray Crystallography, Crystal Structure, Protein Assembly +21

Synthesis of heparin-sepharoses and their binding with thrombin and antithrombin-heparin cofactor

I. Danishefsky, F. Tzeng, M. Ahrens et al. · Thrombosis Research · 1976 · 62 citations

Thrombopoiesis, Thrombosis, Antithrombin-heparin Cofactor +10

Optimization of the β-Aminoester class of factor Xa inhibitors. part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activity

Kevin R. Guertin, Charles J. Gardner, Scott I. Klein et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 52 citations · Full text

Thrombosis, Medicinal Chemistry, Biochemistry +10

Acyclic diastereoselection as a synthetic route to quassinoids: a Claisen rearrangement based strategy for bruceantin

Frederick E. Ziegler, Scott I. Klein, Uttam Pati et al. · Journal of the American Chemical Society · 1985 · 51 citations

Synthetic Route, Bioorganic Chemistry, Altmetric Attention Score +18

Effect of heparin modification on its activity in enhancing the inhibition of thrombin by antithrombin III

I. Danishefsky, M. Ahrens, Scott I. Klein · Biochimica et Biophysica Acta (BBA) - General Subjects · 1977 · 42 citations

Thrombopoiesis, Thrombosis, Biochemistry +10