L G Mendelsohn

LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.

C Shih, V J Chen, Lynn S. Gossett et al. · PubMed · 1997 · 565 citations

Multiple Folate-requiring Enzymes, Medicinal Chemistry, Biochemistry +14

Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis.

L G Mendelsohn, Chwen-Ming Shih, V. J. Chen et al. · PubMed · 1999 · 102 citations

Cell cycle modulation by a multitargeted antifolate, LY231514, increases the cytotoxicity and antitumor activity of gemcitabine in HT29 colon carcinoma.

John L. Tonkinson, John F. Worzalla, C H Teng et al. · PubMed · 1999 · 97 citations

Tumor Biology, Ht29 Colon Carcinoma, Oncology +13

Cell cycle effects of antifolate antimetabolites: implications for cytotoxicity and cytostasis

John L. Tonkinson, Philip Marder, Sherri L. Andis et al. · Cancer Chemotherapy and Pharmacology · 1997 · 82 citations

Biochemistry, Cell Division, Medicine +11

Nasal Delivery of Polypeptides I: Nasal Absorption of Enkephalins in Rats

Kenneth S.E. Su, K. M. Campanale, L G Mendelsohn et al. · Journal of Pharmaceutical Sciences · 1985 · 75 citations

Allergy, Medicine, Pharmacology +3