Taekyu Lee

MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation

Kyung‐min Lee, Jennifer M. Giltnane, Justin M. Balko et al. · Cell Metabolism · 2017 · 625 citations · Full text

Tumor Biology, Breast Oncology, Mitochondrial Function +8

A Novel MCL1 Inhibitor Combined with Venetoclax Rescues Venetoclax-Resistant Acute Myelogenous Leukemia

Haley E. Ramsey, Melissa A. Fischer, Taekyu Lee et al. · Cancer Discovery · 2018 · 355 citations · Full text

Discovery of Potent Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods and Structure-Based Design

Anders Friberg, Dominico Vigil, Bin Zhao et al. · Journal of Medicinal Chemistry · 2012 · 302 citations · Full text

Lead Compounds, Drug Target, Large Fragment Library +16

Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods

Nicholas F. Pelz, Zhiguo Bian, Bin Zhao et al. · Journal of Medicinal Chemistry · 2016 · 143 citations · Full text

Drug Target, Molecular Biology, Tumor Biology +16

Discovery of Tricyclic Indoles That Potently Inhibit Mcl-1 Using Fragment-Based Methods and Structure-Based Design

Jason P. Burke, Zhiguo Bian, Subrata Shaw et al. · Journal of Medicinal Chemistry · 2015 · 95 citations · Full text

Combinatorial Chemistry, Drug Target, Molecular Biology +18