Hiroharu Matsuoka

Discovery of Tofogliflozin, a Novel <i>C</i>-Arylglucoside with an <i>O</i>-Spiroketal Ring System, as a Highly Selective Sodium Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Yoshihito Ohtake, Tsutomu Sato, Takamitsu Kobayashi et al. · Journal of Medicinal Chemistry · 2012 · 168 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Antirheumatic Agents:  Novel Methotrexate Derivatives Bearing a Benzoxazine or Benzothiazine Moiety

Hiroharu Matsuoka, N. OHI, Masahiko Mihara et al. · Journal of Medicinal Chemistry · 1997 · 157 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Discovery of [5-Amino-1-(2-methyl-3<i>H</i>-benzimidazol-5-yl)pyrazol-4-yl]-(1<i>H</i>-indol-2-yl)methanone (CH5183284/Debio 1347), An Orally Available and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor

Hirosato Ebiike, Naoki Taka, Masayuki Matsushita et al. · Journal of Medicinal Chemistry · 2016 · 37 citations · Full text

Medicine, Oncology, Pharmacology +16

Trisubstituted (stannylmethyl)lithium as a methylene double anion equivalent. Reaction with esters

Tadashi Sato, Hiroharu Matsuoka, Tsutomu Igarashi et al. · The Journal of Organic Chemistry · 1988 · 31 citations

Natural Sciences, Chemistry, Analytical Chemistry +4

5a-Carba-β-d-glucopyranose derivatives as novel sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes

Yoshihito Ohtake, Tsutomu Sato, Hiroharu Matsuoka et al. · Bioorganic & Medicinal Chemistry · 2011 · 23 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16