Takamitsu Kobayashi

CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant

Hiroshi Sakamoto, Toshiyuki Tsukaguchi, Sayuri Hiroshima et al. · Cancer Cell · 2011 · 618 citations · Full text

Molecular Pharmacology, Resistant Gatekeeper Mutant, Drug Discovery +8

Discovery of Tofogliflozin, a Novel <i>C</i>-Arylglucoside with an <i>O</i>-Spiroketal Ring System, as a Highly Selective Sodium Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Yoshihito Ohtake, Tsutomu Sato, Takamitsu Kobayashi et al. · Journal of Medicinal Chemistry · 2012 · 165 citations · Full text

Chemical Biology, Pharmaceutical Chemistry, Molecular Pharmacology +16

Tofogliflozin, a Potent and Highly Specific Sodium/Glucose Cotransporter 2 Inhibitor, Improves Glycemic Control in Diabetic Rats and Mice

Masayuki Suzuki, Kiyofumi Honda, Masanori Fukazawa et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 164 citations

Design and synthesis of a highly selective, orally active and potent anaplastic lymphoma kinase inhibitor (CH5424802)

Kazutomo Kinoshita, Kohsuke Asoh, Noriyuki Furuichi et al. · Bioorganic & Medicinal Chemistry · 2011 · 163 citations · Full text

Chemoprevention Strategy, Medicine, Anti-cancer Agent +3

Microbially induced calcite precipitation for production of “bio-bricks” treated at partial saturation condition

Liang Cheng, Takamitsu Kobayashi, Mohamed A. Shahin · Construction and Building Materials · 2019 · 85 citations

Biomanufacturing, Biochar, Engineering +10