Kohsuke Asoh

Design and synthesis of a highly selective, orally active and potent anaplastic lymphoma kinase inhibitor (CH5424802)

Kazutomo Kinoshita, Kohsuke Asoh, Noriyuki Furuichi et al. · Bioorganic & Medicinal Chemistry · 2011 · 164 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +8

9-Substituted 6,6-Dimethyl-11-oxo-6,11-dihydro-5<i>H</i>-benzo[<i>b</i>]carbazoles as Highly Selective and Potent Anaplastic Lymphoma Kinase Inhibitors

Kazutomo Kinoshita, Takamitsu Kobayashi, Kohsuke Asoh et al. · Journal of Medicinal Chemistry · 2011 · 84 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent

Yoshiaki Isshiki, Yasunori Kohchi, Hitoshi Iikura et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 77 citations · Full text

Pharmacy, Oncology, Pharmacology +13

Synthesis and structure–activity relationships of novel benzofuran farnesyltransferase inhibitors

Kohsuke Asoh, Masami Kohchi, Ikumi Hyoudoh et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 41 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery of novel tetracyclic compounds as anaplastic lymphoma kinase inhibitors

Kazutomo Kinoshita, Yoshiyuki Ono, Takashi Emura et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 37 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +14