Kohsuke Asoh

Design and synthesis of a highly selective, orally active and potent anaplastic lymphoma kinase inhibitor (CH5424802)

Kazutomo Kinoshita, Kohsuke Asoh, Noriyuki Furuichi et al. · Bioorganic & Medicinal Chemistry · 2011 · 163 citations · Full text

Chemoprevention Strategy, Medicine, Anti-cancer Agent +3

9-Substituted 6,6-Dimethyl-11-oxo-6,11-dihydro-5<i>H</i>-benzo[<i>b</i>]carbazoles as Highly Selective and Potent Anaplastic Lymphoma Kinase Inhibitors

Kazutomo Kinoshita, Takamitsu Kobayashi, Kohsuke Asoh et al. · Journal of Medicinal Chemistry · 2011 · 83 citations · Full text

Compound 13D, Molecular Pharmacology, Medicinal Chemistry +12

Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent

Yoshiaki Isshiki, Yasunori Kohchi, Hitoshi Iikura et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 76 citations · Full text

Medicinal Chemistry, Medicine, Available Anticancer Agent +6

Synthesis and structure–activity relationships of novel benzofuran farnesyltransferase inhibitors

Kohsuke Asoh, Masami Kohchi, Ikumi Hyoudoh et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 40 citations · Full text

Medicinal Chemistry, Medicine, Structure–activity Relationships +3

Discovery of novel tetracyclic compounds as anaplastic lymphoma kinase inhibitors

Kazutomo Kinoshita, Yoshiyuki Ono, Takashi Emura et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 35 citations · Full text

Medicine, Novel Tetracyclic Compounds, Anti-cancer Agent +4