Yoshiaki Isshiki

Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments

Leo A. Hardegger, Bernd Kuhn, Beat Spinnler et al. · ChemMedChem · 2011 · 128 citations

Design, synthesis and antifungal activity of a novel water soluble prodrug of antifungal triazole

Jun Ohwada, Masao Tsukazaki, Tadakatsu Hayase et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 82 citations

Antifungal Agent, Antifungal Activity, Antifungal Agents +7

Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent

Yoshiaki Isshiki, Yasunori Kohchi, Hitoshi Iikura et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 76 citations · Full text

Medicinal Chemistry, Medicine, Available Anticancer Agent +6

Synthesis and structure–activity relationships of novel fungal chitin synthase inhibitors

Kazunao Masubuchi, Mikio Taniguchi, Isao UMEDA et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 42 citations · Full text

Biosynthesis, Antifungal Agent, Biochemistry +6

Design and synthesis of 2-amino-6-(1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazines as novel Hsp90 inhibitors

Atsushi Suda, Ken‐ichi Kawasaki, Susumu Komiyama et al. · Bioorganic & Medicinal Chemistry · 2013 · 40 citations · Full text