Michael A. Ackley - Concepedia

Author

Michael A. Ackley

Sage Therapeutics (United States)

Also Known As

Ackley, Michael A., M. A Ackley, M. A. Ackley, M.A. Ackley, Michael A. Ackley, Michael Ackley

Publications

1.1K

Citations

H-Index

Concepts

All Affiliations

Sage Therapeutics (United States)Tufts University University of Leeds University College London WuXi AppTec (China)

About

Michael A. Ackley is an author at Sage Therapeutics (United States) specializing in neuroscience, medicine, and central nervous system.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	183
2	Social Sciences	3	3	95
3	Health Sciences	2	2	74
4	Anesthesia	1	1	59
5	Endocrinology	1	1	23

Michael A. Ackley

Publications

761

Citations

H-Index

Page 1

	Year	Citations
Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABAA receptor positive allosteric modulator Alison L. Althaus, Michael A. Ackley, Gabriel M. Belfort, Neuropharmacology	2020	120
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1 <i>H</i> -pyrazol-1′-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid) <sub>A</sub> Receptor Gabriel Martinez Botella, Francesco G. Salituro, Boyd L. Harrison, Journal of Medicinal Chemistry	2017	119
Endogenous and synthetic neuroactive steroids evoke sustained increases in the efficacy of GABAergic inhibition via a protein kinase C-dependent mechanism Amit Modgil, Manasa L. Parakala, Michael A. Ackley, Neuropharmacology	2016	76
A cellular mechanism for the antinociceptive effect of a kappa opioid receptor agonist Michael A. Ackley, Robert W. Hurley, Daniel E. Virnich, Pain Pain MedicineSynaptic TransmissionNeurotransmitterPaw-withdrawal LatencyMolecular Pain	2001	59
Control of glutamatergic neurotransmission in the rat spinal dorsal horn by the nucleoside transporter ENT1 Michael A. Ackley, Ricardo Jose Moylan Governo, Carol E. Cass, The Journal of Physiology Rat Spinal DorsalSynaptic TransmissionNeurotransmitterMolecular PainNeurotransmission	2003	58
Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid) <sub>A</sub> Receptor: Structure–Activity Relationships of Heterocyclic Substitution at C-21 Gabriel Martinez Botella, Francesco G. Salituro, Boyd L. Harrison, Journal of Medicinal Chemistry	2015	53
Control of glutamatergic neurotransmission in the rat spinal dorsal horn by the nucleoside transporter ENT1 Michael A. Ackley, Ricardo Jose Moylan Governo, Carol E. Cass, The Journal of Physiology	2003	51
Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABAA receptors Manasa L. Parakala, Yihui Zhang, Amit Modgil, Journal of Biological Chemistry	2019	49
SAGE-718: A First-in-Class<i>N</i>-Methyl-<scp>d</scp>-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment Matthew D. Hill, María‐Jesús Blanco, Francesco G. Salituro, Journal of Medicinal Chemistry	2022	39
Anticonvulsant profile of the neuroactive steroid, SGE-516, in animal models Rebecca Hammond, Alison L. Althaus, Michael A. Ackley, Epilepsy Research Neuroactive SteroidNeurophysiologyMedicineNeuroendocrine MechanismNeuropharmacology	2017	23

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