Concepedia

Michael A. Ackley

MA

18

Publications

761

Citations

14

H-Index

1997

Active since

Affiliations

Sage Therapeutics (United States)(Current)

Tufts University

University of Leeds

University College London

WuXi AppTec (China)

Michael A. Ackley is an author at Sage Therapeutics (United States) specializing in neuroscience, medicine, and central nervous system.

Top concepts

Publications per year

1997–2023

18

Publications

18

Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABAA receptor positive allosteric modulator

Alison L. Althaus, Michael A. Ackley, Gabriel M. Belfort et al. · Neuropharmacology · 2020 · 120 citations · Full text

Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1 <i>H</i> -pyrazol-1′-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid) <sub>A</sub> Receptor

Gabriel Martinez Botella, Francesco G. Salituro, Boyd L. Harrison et al. · Journal of Medicinal Chemistry · 2017 · 119 citations · Full text

Endogenous and synthetic neuroactive steroids evoke sustained increases in the efficacy of GABAergic inhibition via a protein kinase C-dependent mechanism

Amit Modgil, Manasa L. Parakala, Michael A. Ackley et al. · Neuropharmacology · 2016 · 76 citations · Full text

A cellular mechanism for the antinociceptive effect of a kappa opioid receptor agonist

Michael A. Ackley, Robert W. Hurley, Daniel E. Virnich et al. · Pain · 2001 · 59 citations

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Control of glutamatergic neurotransmission in the rat spinal dorsal horn by the nucleoside transporter ENT1

Michael A. Ackley, Ricardo Jose Moylan Governo, Carol E. Cass et al. · The Journal of Physiology · 2003 · 58 citations

, , +22

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