Concepedia

Gabriel Martinez Botella

GM

5

Publications

237

Citations

5

H-Index

2015

Active since

Affiliations

Sage Therapeutics (United States)(Current)

WuXi AppTec (China)

Gabriel Martinez Botella is an author at Sage Therapeutics (United States) specializing in neurophysiology, neurochemistry, and endocrinology.

Top concepts

Publications per year

2015–2022

5

Publications

5

Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1 <i>H</i> -pyrazol-1′-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid) <sub>A</sub> Receptor

Gabriel Martinez Botella, Francesco G. Salituro, Boyd L. Harrison et al. · Journal of Medicinal Chemistry · 2017 · 119 citations · Full text

Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid) <sub>A</sub> Receptor: Structure–Activity Relationships of Heterocyclic Substitution at C-21

Gabriel Martinez Botella, Francesco G. Salituro, Boyd L. Harrison et al. · Journal of Medicinal Chemistry · 2015 · 53 citations

The novel persistent sodium current inhibitor PRAX‐562 has potent anticonvulsant activity with improved protective index relative to standard of care sodium channel blockers

Kristopher M. Kahlig, Liam Scott, Robert J. Hatch et al. · Epilepsia · 2022 · 27 citations · Full text

Anticonvulsant profile of the neuroactive steroid, SGE-516, in animal models

Rebecca Hammond, Alison L. Althaus, Michael A. Ackley et al. · Epilepsy Research · 2017 · 23 citations

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Neuroactive Steroid <i>N</i>-Methyl-<scp>d</scp>-aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological Activity

Daniel S. La, Francesco G. Salituro, Gabriel Martinez Botella et al. · Journal of Medicinal Chemistry · 2019 · 15 citations · Full text

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