Alison L. Althaus

Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABAA receptor positive allosteric modulator

Alison L. Althaus, Michael A. Ackley, Gabriel M. Belfort et al. · Neuropharmacology · 2020 · 128 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1 <i>H</i> -pyrazol-1′-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid) _A Receptor

Gabriel Martinez Botella, Francesco G. Salituro, Boyd L. Harrison et al. · Journal of Medicinal Chemistry · 2017 · 123 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Axonal plasticity of age-defined dentate granule cells in a rat model of mesial temporal lobe epilepsy

Alison L. Althaus, Honghao Zhang, Jack M. Parent · Neurobiology of Disease · 2015 · 50 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Intrinsic neurophysiological properties of hilar ectopic and normotopic dentate granule cells in human temporal lobe epilepsy and a rat model

Alison L. Althaus, Oren Sagher, Jack M. Parent et al. · Journal of Neurophysiology · 2014 · 45 citations

Medicine, Neurobiology, Neuroscience +15

Altered Synaptic Drive onto Birthdated Dentate Granule Cells in Experimental Temporal Lobe Epilepsy

Alison L. Althaus, Shannon J. Moore, Helen Zhang et al. · Journal of Neuroscience · 2019 · 39 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17