Raffaella Mangano

A physical and functional map of the human TNF-α/NF-κB signal transduction pathway

Tewis Bouwmeester, Angela Bauch, Heinz Ruffner et al. · Nature Cell Biology · 2004 · 1K citations

Inflammation, Transcriptional Regulation, Molecular Physiology +14

Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with advanced ovarian and breast cancer

Yvette Drew, Jonathan A. Ledermann, Geoff Hall et al. · British Journal of Cancer · 2016 · 161 citations · Full text

A selective inhibitor reveals PI3Kγ dependence of TH17 cell differentiation

Giovanna Bergamini, Kathryn M. Bell, Satoko Shimamura et al. · Nature Chemical Biology · 2012 · 143 citations

Signal Transduction, Signaling Pathway, Cell Regulation +7

A nuclear tyrosine phosphorylation circuit: c-Jun as an activator and substrate of c-Abl and JNK

Daniela Barilá, Raffaella Mangano, Stefania Gonfloni et al. · The EMBO Journal · 2000 · 84 citations · Full text

Signal Transduction, Signaling Pathway, Biochemistry +9

Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists

Sue Cramp, Hazel J. Dyke, Christopher Higgs et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 27 citations · Full text

Drug Target, Novel Series, Biochemistry +9