Heinz Ruffner

Functional organization of the yeast proteome by systematic analysis of protein complexes

Anne‐Claude Gavin, Markus Bösche, Roland Krause et al. · Nature · 2002 · 4.8K citations · Full text

Yeast Proteome, Biochemistry, Protein Folding +10

A physical and functional map of the human TNF-α/NF-κB signal transduction pathway

Tewis Bouwmeester, Angela Bauch, Heinz Ruffner et al. · Nature Cell Biology · 2004 · 1K citations

Inflammation, Transcriptional Regulation, Molecular Physiology +14

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

Huai-Xiang Hao, Yang Xie, Yue Zhang et al. · Nature · 2012 · 955 citations

Sclerostin, Signal Transduction, Signaling Pathway +5

Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

Heinz Ruffner, Claudio A.P. Joazeiro, Dan Hemmati et al. · Proceedings of the National Academy of Sciences · 2001 · 361 citations · Full text

The RSPO–LGR4/5–ZNRF3/RNF43 module controls liver zonation and size

Lara Planas‐Paz, Vanessa Orsini, Luke Boulter et al. · Nature Cell Biology · 2016 · 348 citations · Full text

Molecular Physiology, Hepatology, Liver Physiology +7