Concepedia

Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists

Sue Cramp, Hazel J. Dyke, Christopher Higgs, David E. Clark, Matthew Gill, Pascal Savy, Neil Jennings, Steve Price, Peter Lockey, Dennis Norman,

Bioorganic & Medicinal Chemistry Letters · 2010 · 27 citations · 5 references

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References

5

The First Potent and Selective Non-Imidazole Human Histamine H<sub>4</sub>Receptor Antagonists

Jill A. Jablonowski, Cheryl A. Grice, Wenying Chai et al. · Journal of Medicinal Chemistry · 2003 · 196 citations · Full text

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Rotationally Constrained 2,4-Diamino-5,6-disubstituted Pyrimidines: A New Class of Histamine H<sub>4</sub>Receptor Antagonists with Improved Druglikeness and in Vivo Efficacy in Pain and Inflammation Models

Marlon Cowart, Robert J. Altenbach, Huaqing Liu et al. · Journal of Medicinal Chemistry · 2008 · 82 citations · Full text

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A Virtual Screening Approach to Finding Novel and Potent Antagonists at the Melanin-Concentrating Hormone 1 Receptor

David E. Clark, Christopher Higgs, Stephen P. Wren et al. · Journal of Medicinal Chemistry · 2004 · 79 citations · Full text

, , +17

Structure–activity relationships of a novel series of melanin-concentrating hormone (MCH) receptor antagonists

Rosa Arienzo, David E. Clark, Sue Cramp et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 42 citations · Full text

, , +15

Quinazoline and benzimidazole MCH-1R antagonists

Rosa Arienzo, Sue Cramp, Hazel J. Dyke et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 23 citations · Full text

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