Robert J. Altenbach

Rotationally Constrained 2,4-Diamino-5,6-disubstituted Pyrimidines: A New Class of Histamine H₄Receptor Antagonists with Improved Druglikeness and in Vivo Efficacy in Pain and Inflammation Models

Marlon Cowart, Robert J. Altenbach, Huaqing Liu et al. · Journal of Medicinal Chemistry · 2008 · 81 citations · Full text

Structure−Activity Studies on a Series of a 2-Aminopyrimidine-Containing Histamine H₄Receptor Ligands

Robert J. Altenbach, Ronald M. Adair, Brian M. Bettencourt et al. · Journal of Medicinal Chemistry · 2008 · 58 citations · Full text

2,3-Diarylindenes and 2,3-diarylindenones: synthesis, molecular structure, photochemistry, estrogen receptor binding affinity, and comparisons with related triarylethylenes

Gregory M. Anstead, Robert J. Altenbach, Scott R. Wilson et al. · Journal of Medicinal Chemistry · 1988 · 51 citations

<i>cis</i>-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-<i>h</i>]quinazolin-2-amine (A-987306), A New Histamine H₄R Antagonist that Blocks Pain Responses against Carrageenan-Induced Hyperalgesia

Huaqing Liu, Robert J. Altenbach, Tracy L. Carr et al. · Journal of Medicinal Chemistry · 2008 · 48 citations · Full text

Pain Disorders, Pain Medicine, Immunology +21

Synthesis and Structure−Activity Relationships of a Novel Series of 2,3,5,6,7,9-Hexahydrothieno[3,2-<i>b</i>]quinolin-8(4<i>H</i>)-one 1,1-Dioxide K_ATP Channel Openers:  Discovery of (−)-(9<i>S</i>)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9- hexahydrothieno[3,2-<i>b</i>]quinolin-8(4<i>H</i>)-one 1,1-Dioxide (A-278637), a Potent K_ATP Opener That Selectively Inhibits Spontaneous Bladder Contractions

William A. Carroll, Robert J. Altenbach, Hao Bai et al. · Journal of Medicinal Chemistry · 2004 · 44 citations

Spontaneous Bladder Contractions, Bioorganic Chemistry, Compound 14 +18