Kurt R. Auger

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

Mark A. Dawson, Rab K. Prinjha, Antje Dittmann et al. · Nature · 2011 · 1.5K citations · Full text

Hematological Malignancy, Chromatin, Bet Recruitment +11

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

Kurt R. Auger, Leslie A. Serunian, Stephen P. Soltoff et al. · Cell · 1989 · 924 citations

Intact Cells, Signal Transduction, Developmental Biology +10

Transformation of Chicken Cells by the Gene Encoding the Catalytic Subunit of PI 3-Kinase

Hwai Wen Chang, Masahiro Aoki, David Fruman et al. · Science · 1997 · 415 citations

Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin

Steven D. Knight, Nicholas D. Adams, Joelle L. Burgess et al. · ACS Medicinal Chemistry Letters · 2010 · 367 citations · Full text

Highly Potent Inhibitor, Tumor Biology, Mammalian Target +16

BET Inhibition Silences Expression of MYCN and BCL2 and Induces Cytotoxicity in Neuroblastoma Tumor Models

Anastasia Wyce, Gopinath Ganji, Kimberly N. Smitheman et al. · PLoS ONE · 2013 · 203 citations · Full text

Mycn Copy Number, Bet Family Proteins, Cell Regulation +14