Steven D. Knight

Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2

Sharad K. Verma, Xinrong Tian, Louis V. LaFrance et al. · ACS Medicinal Chemistry Letters · 2012 · 373 citations · Full text

Histone Modifications, Drug Discovery Program, Engineering +18

Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin

Steven D. Knight, Nicholas D. Adams, Joelle L. Burgess et al. · ACS Medicinal Chemistry Letters · 2010 · 367 citations · Full text

Highly Potent Inhibitor, Tumor Biology, Mammalian Target +16

Antitumor activity of an allosteric inhibitor of centromere-associated protein-E

Kenneth W. Wood, Latesh Lad, Lusong Luo et al. · Proceedings of the National Academy of Sciences · 2010 · 252 citations · Full text

Antitumor Activity, Cenp-e Motor Activity, Molecular Biology +18

Synthesis applications of cationic aza-Cope rearrangements. 26. Enantioselective total synthesis of (-)-strychnine

Steven D. Knight, Larry E. Overman, Garry Pairaudeau · Journal of the American Chemical Society · 1993 · 171 citations

Cationic Aza-cope Rearrangements, Chemical Analysis, Natural Sciences +13

Asymmetric Total Syntheses of (-)- and (+)-Strychnine and the Wieland-Gumlich Aldehyde

Steven D. Knight, Larry E. Overman, Garry Pairaudeau · Journal of the American Chemical Society · 1995 · 140 citations

Engineering, Chemical Analysis, Altmetric Attention Score +17