Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells

Bing‐Hua Jiang, Jenny Z. Zheng, Masahiro Aoki, +1

Proceedings of the National Academy of Sciences

Transformation of Chicken Cells by the Gene Encoding the Catalytic Subunit of PI 3-Kinase

Hwai Wen Chang, Masahiro Aoki, David Fruman, +6

Science

Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC

Kiyotoshi Satoh, Shinichi Yachida, Masahiro Sugimoto, +24

Proceedings of the National Academy of Sciences

The Akt kinase: Molecular determinants of oncogenicity

Masahiro Aoki, Osvaldo Batista, Alfonso Bellacosa, +2

Proceedings of the National Academy of Sciences

A role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt

Masahiro Aoki, Erik Blazek, Peter K. Vogt

Proceedings of the National Academy of Sciences

Tumor BiologySignaling PathwayCell RegulationReceptor Tyrosine KinaseCellular Regulatory Mechanism +15

SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion

Takanori Kitamura, Kohei Kometani, Hiroki Hashida, +9

Nature Genetics

Tumor BiologyMedicineImmunologyPathologyColorectal Cancer +5

Activated macrophages promote Wnt signalling through tumour necrosis factor-α in gastric tumour cells

K. Oguma, Hiroko Oshima, Masahiro Aoki, +7

The EMBO Journal

InflammationSignaling PathwayImmunologyImmune RegulationChronic Inflammation +8

Myogenic signaling of phosphatidylinositol 3-kinase requires the serine-threonine kinase Akt/protein kinase B

Bing‐Hua Jiang, Masahiro Aoki, Jenny Z. Zheng, +2

Proceedings of the National Academy of Sciences

Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteins

Masahiro Aoki, Hao Jiang, Peter K. Vogt

Proceedings of the National Academy of Sciences

Suppression of Colon Cancer Metastasis by Aes through Inhibition of Notch Signaling

Masahiro Sonoshita, Masahiro Aoki, Haruhiko Fuwa, +13

Cancer Cell

Signaling PathwayMedicineColon Cancer MetastasisTumor SuppressorRadiation Oncology +5