Kenji Kuwabara

The Role of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Antibody-Induced Arthritis

Takeshi Itoh, Hidetoshi Matsuda, Masatoshi Tanioka et al. · The Journal of Immunology · 2002 · 305 citations

Immunology, Pathology, Matrix Metalloproteinase-2 +21

2-{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304), an Orally Available and Long-Acting Prostacyclin Receptor Agonist Prodrug

Keiichi Kuwano, Asami Hashino, Tetsuo Asaki et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 160 citations

A Long-Acting and Highly Selective Prostacyclin Receptor Agonist Prodrug, 2-{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304), Ameliorates Rat Pulmonary Hypertension with Unique Relaxant Responses of Its Active Form, {4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}acetic Acid (MRE-269), on Rat Pulmonary Artery

Keiichi Kuwano, Asami Hashino, Kumiko Noda et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 87 citations

Crucial Role of Group IIA Phospholipase A ₂ in Oleic Acid–Induced Acute Lung Injury in Rabbits

S. Furue, Kenji Kuwabara, Katsuya Mikawa et al. · American Journal of Respiratory and Critical Care Medicine · 1999 · 69 citations

Therapeutic time-window of a group IIA phospholipase A2 inhibitor in rabbit acute lung injury: Correlation with lung surfactant protection

S. Furue, Katsuya Mikawa, Kahoru Nishina et al. · Critical Care Medicine · 2001 · 60 citations