Keiichi Kuwano - Concepedia

Author

Keiichi Kuwano

Nippon Shinyaku (Japan)

Also Known As

Keiichi Kuwano

Publications

425

Citations

H-Index

Concepts

All Affiliations

Nippon Shinyaku (Japan)

About

Keiichi Kuwano is an author at Nippon Shinyaku (Japan) specializing in medicine, pharmacotherapy, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	165
2	Pharmacology	4	4	165
3	Public Health	2	2	97
4	Biochemistry	2	2	136
5	Pulmonary Medicine	1	1	86

Keiichi Kuwano

Publications

412

Citations

H-Index

Page 1

	Year	Citations
2-{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304), an Orally Available and Long-Acting Prostacyclin Receptor Agonist Prodrug Keiichi Kuwano, Asami Hashino, Tetsuo Asaki, Journal of Pharmacology and Experimental Therapeutics	2007	160
A Long-Acting and Highly Selective Prostacyclin Receptor Agonist Prodrug, 2-{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304), Ameliorates Rat Pulmonary Hypertension with Unique Relaxant Responses of Its Active Form, {4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}acetic Acid (MRE-269), on Rat Pulmonary Artery Keiichi Kuwano, Asami Hashino, Kumiko Noda, Journal of Pharmacology and Experimental Therapeutics	2008	87
Selexipag: An Oral and Selective IP Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension Tetsuo Asaki, Keiichi Kuwano, Keith Morrison, Journal of Medicinal Chemistry HypertensionCardiovascular PharmacologyPharmacotherapyPharmaceutical ChemistryMolecular Pharmacology	2015	86
Structure–activity studies on diphenylpyrazine derivatives: A novel class of prostacyclin receptor agonists Tetsuo Asaki, Taisuke Hamamoto, Yukiteru Sugiyama, Bioorganic & Medicinal Chemistry Prostacyclin Receptor AgonistsMolecular PharmacologyDiphenylpyrazine DerivativesDerivativesStructure–activity Studies	2007	50
A comparison of vasodilation mode among selexipag (NS-304; [2-{4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide]), its active metabolite MRE-269 and various prostacyclin receptor agonists in rat, porcine and human pulmonary arteries Chiaki Fuchikami, Kohji Murakami, Koyuki Tajima, European Journal of Pharmacology Medicinal ChemistryVasodilation ModeMedicineVascular PharmacologyPhysiology	2016	18
The selective PGI2 receptor agonist selexipag ameliorates Sugen 5416/hypoxia-induced pulmonary arterial hypertension in rats Yohei Honda, Keiji Kosugi, Chiaki Fuchikami, PLoS ONE HypertensionHeart FailurePulmonary Arterial HypertensionPulmonary CirculationCardiovascular Disease	2020	11

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